Brent Ferrell

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SurA is the primary periplasmic molecular chaperone that facilitates the folding and assembling of outer membrane proteins (OMPs) in Gram-negative bacteria. Deletion of the surA gene in Escherichia coli leads to a decrease in outer membrane density and an increase in bacterial drug susceptibility. Here, we conducted mutational studies on SurA to identify(More)
SurA is a major periplasmic molecular chaperone in Escherichia coli and has been shown to assist the biogenesis of several outer membrane proteins. The C-terminal fragment of SurA folds into a short β-strand, which forms a small three-stranded anti-parallel β-sheet module with the N-terminal β-hairpin. We found that the length of the C-terminal fragment,(More)
  • B C Ferrell
  • Compendium of continuing education in dentistry
  • 2001
The popularity of esthetic dentistry has transformed the traditional dental practice. Anterior tooth restorations impact the beauty of a smile as well as the function of the entire dentition. The long-term success of esthetic restorations can be improved by controlling the occlusal forces to which they are subjected. During sleep and periods of intense(More)
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