Brendan Francis O'Connor

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The in situ preparation of ethylene dimethacrylate porous polymer monoliths within 20 μL polypropylene pipette tips, bound via surface grafted methacrylate anchor sites, is reported. Gold nano-particles (AuNPs) were immobilised onto the monolith pore surface utilising azlactone chemistry and coverage verified using field emission scanning electron(More)
Most proteins and large polypeptides have hydrophobic regions at their surface. These hydrophobic "patches" are due to the presence of the side chains of hydrophobic or nonpolar amino acids such as phenylalanine, tryptophan, alanine, and methionine. These surface hydrophobic regions are interspersed between more hydrophilic or polar regions and the number,(More)
BACKGROUND The mammalian heme peroxidases (MHPs) are a medically important group of enzymes. Included in this group are myeloperoxidase, eosinophil peroxidase, lactoperoxidase, and thyroid peroxidase. These enzymes are associated with such diverse diseases as asthma, Alzheimer's disease and inflammatory vascular disease. Despite much effort to elucidate a(More)
OBJECTIVE To describe three cases of delayed development of intracranial hypertension (IH) after surgical treatment of intracranial arachnoid cyst, including the pathogenesis of IH and a review of the literature. METHODS A retrospective and prospective analysis of three male patients (two 18 years old and one 45 years old) was performed. All patients(More)
Reputation forms an important part of how we come to trust people in face-to-face interactions, and thus situations involving trust online have come to realize that reputation is an important characteristic in the digital age. We propose a new holistic and context-free approach to quantifying reputation on the Internet, based upon a stock exchange where(More)
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