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Confabulation and amnesia are considered disorders of episodic but not of semantic memory. To test the limits of this view, retrieval from episodic and semantic memory was investigated in eight confabulating and nine non-confabulating amnesic subjects, and in 17 matched control subjects, by using a personal and an historical version of the Crovitz(More)
The 'temporality' hypothesis of confabulation posits that confabulations are true memories displaced in time, while the 'strategic retrieval' hypothesis suggests a general retrieval failure of which temporal confusion is a common symptom. Four confabulating patients with rupture of an anterior communicating artery (ACoA) aneurysm, eight non-confabulating(More)
Estimation of premorbid IQ in traumatic brain injury (TBI) is clinically and scientifically valuable because it permits the quantification of the cognitive impact of injury. This is achieved by comparing performances on tests of current ability to estimates of premorbid IQ, thereby enabling current capacity to be interpreted in light of preinjury ability.(More)
This study examines the ability of amnesic patients to recover newly formed associations implicitly after a single study trial. Fifteen amnesic patients with various etiologies studied pairs by forming a sentence containing both words. At test, all participants saw 40 intact pairs, 40 rearranged pairs, and 40 new words. All pairs appeared side by side both(More)
Three experiments were conducted to determine whether encoding processes that support episodic memory for object location are distinct from those that support memory for object identity. Guided by transfer-appropriate processing notions, we examined with an incidental learning paradigm whether an attentional focus on object location at encoding promotes(More)
The status of neurorehabilitation for traumatic brain injury (TBI) is under active debate because of a dearth of research findings demonstrating effectiveness. This may be due, in part, to limitations in our understanding of basic mechanisms of cognitive and motor recovery,including those that might impede recovery. In this regard, we examined whether(More)
We examined preliminarily whether intensive mental activity can transiently enhance higher cognitive functioning in healthy adults. Ten healthy participants performed intensive mental activity for 2 weeks. The intervention entailed daily memorization of multiple prose passages and performance of demanding, speeded mental arithmetic.Neuropsychological(More)
ATP, via activation of P2X3 receptors, has been highlighted as a key target in inflammatory hyperalgesia. Therefore, the aim of this study was to confirm whether the activation of P2X3 receptors in the gastrocnemius muscle of rats induces mechanical muscle hyperalgesia and, if so, to analyze the involvement of the classical inflammatory mediators(More)
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