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OBJECTIVE To compare the operative outcomes of early and delayed cholecystectomy for acute cholecystitis. BACKGROUND Randomized trials comparing early to delayed cholecystectomy for acute cholecystitis have limited contemporary external validity. Furthermore, no study to date has been large enough to assess the impact of timing of cholecystectomy on the(More)
OBJECTIVES We determined the proportion of workers meeting criteria for major depressive episodes in the past year and examined the association between psychosocial work-stress variables and these episodes. METHODS Data were derived from the Canadian Community Health Survey 1.2, a population-based survey of 24324 employed, community-dwelling individuals(More)
BACKGROUND The aim of this paper is to examine factors associated with discharge destination after acquired brain injury in a publicly insured population using the Anderson Behavioral Model as a framework. METHODS We utilized a retrospective cohort design. Inpatient data from provincial acute care records from fiscal years 2003/4 to 2006/7 with a(More)
BACKGROUND Despite evidence in favour of early cholecystectomy for most patients with acute cholecystitis, variation in practice has been reported across hospitals worldwide. We sought to characterize the extent and potential sources of variation in the performance of early cholecystectomy for acute cholecystitis within a large regional health care system.(More)
OBJECTIVE To evaluate the effectiveness of the community based Cardiovascular Health Awareness Program (CHAP) on morbidity from cardiovascular disease. DESIGN Community cluster randomised trial. SETTING 39 mid-sized communities in Ontario, Canada, stratified by location and population size. PARTICIPANTS Community dwelling residents aged 65 years or(More)
OBJECTIVE We sought to validate a case-finding algorithm for human immunodeficiency virus (HIV) infection using administrative health databases in Ontario, Canada. METHODS We constructed 48 case-finding algorithms using combinations of physician billing claims, hospital and emergency room separations and prescription drug claims. We determined the test(More)
OBJECTIVE To assess whether antidepressant treatment is associated with a temporary increase in the risk of a motor vehicle crash among older adults. DESIGN Population-based case-only time-to-event analysis. SETTING AND SUBJECTS Data from transportation and healthcare databases for adults age 65 and older in Ontario, Canada, between January 1, 2000, and(More)
BACKGROUND Disease-specific estimates of medical costs are important for health policy decision making. OBJECTIVE To identify predictors of health care costs associated with hepatitis C virus (HCV) seropositivity across disease phases. METHODS HCV laboratory tests from the BC Centre for Disease Control were linked to administrative data pertaining to(More)
With increasing emphasis on the provision of home-based palliative care in Canada, economic evaluation is warranted, given its tremendous demands on family caregivers. Despite this, very little is known about the economic outcomes associated with home-based unpaid care-giving at the end of life. The aims of this study were to (i) assess the magnitude and(More)
PURPOSE The Canadian STOP-PAIN Project was designed to document the human and economic burden of chronic pain in individuals on waitlists of Multidisciplinary Pain Treatment Facilities (MPTF). This paper describes the societal costs of their pain. METHODS A subgroup of 370 patients was selected randomly from The Canadian STOP-PAIN Project. Participants(More)