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  • Brandon J Henderson, Teagan R Wall, +5 authors Henry A. Lester
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2016 (First Published: 9 March 2016)
  • Upregulation of β2 subunit-containing (β2*) nicotinic acetylcholine receptors (nAChRs) is implicated in several aspects of nicotine addiction, and menthol cigarette smokers tend to upregulate β2*Continue Reading
  • Brandon J Henderson, Teagan R Wall, Beverley Henley, Charlene H. Kim, Sheri L McKinney, Henry A. Lester
  • Psychology, Medicine
  • Neuropsychopharmacology
  • 2017 (First Published: 1 November 2017)
  • Understanding why the quit rate among smokers of menthol cigarettes is lower than non-menthol smokers requires identifying the neurons that are altered by nicotine, menthol, and acetylcholine.Continue Reading
  • Weston A. Nichols, Brandon J Henderson, +4 authors Julie M. Miwa
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2014 (First Published: 5 September 2014)
  • Background: lynx1 reduces sensitivity of α4β2 nAChRs in vitro and also reduces nicotinic responses in vivo. Results: The GPI protein, lynx1, affects α4/α4 dimer formation in the ER, altering plasmaContinue Reading
  • Tatiana F. González-Cestari, Brandon J Henderson, +10 authors D. B. Mckay
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 2009 (First Published: 1 February 2009)
  • Allosteric modulation of nAChRs is considered to be one of the most promising approaches for drug design targeting nicotinic acetylcholine receptors (nAChRs). We have reported previously on theContinue Reading
  • Brandon J Henderson, Crina M. Orac, Iwona Maciągiewicz, Stephen C. Bergmeier, D. B. Mckay
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2012 (First Published: 1 February 2012)
  • Subtype selective molecules for α4β2 neuronal nicotinic acetylcholine receptors (nAChRs) have been sought as novel therapeutics for nicotine cessation. α4β2 nAChRs have been shown to be involved inContinue Reading