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Erythropoietin: Powerful protection of ischemic and post-ischemic brain
Ischemic brain injury inflicted by stroke and cardiac arrest ranks among the leading causes of death and long-term disability in the United States. The brain consumes large amounts of metabolicExpand
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Mineralocorticoid receptor in the NTS stimulates saline intake during fourth ventricular infusions of aldosterone.
The purpose of this study was to determine whether neurons within the nucleus tractus solitarius (NTS) that express the mineralocorticoid receptor (MR) play a role in aldosterone stimulation of saltExpand
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Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest
Cardiac arrest (CA) and cardiocerebral resuscitation (CCR)-induced ischemia–reperfusion imposes oxidative and carbonyl stress that injures the brain. The ischemic shift to anaerobic glycolysis,Expand
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Modeling cardiac arrest and resuscitation in the domestic pig.
Cardiac arrest remains a leading cause of death and permanent disability worldwide. Although many victims are initially resuscitated, they often succumb to the extensive ischemia-reperfusion injuryExpand
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Pyruvate stabilizes electrocardiographic and hemodynamic function in pigs recovering from cardiac arrest
Cardiac electromechanical dysfunction may compromise recovery of patients who are initially resuscitated from cardiac arrest, and effective treatments remain elusive. Pyruvate, a natural intermediaryExpand
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Vasopressin instead of epinephrine enhances efficacy of CPR without causing tachycardia (1150.5)
Survival from cardiac arrest is highly dependent on the arterial pressure generated by cardiopulmonary resuscitation (CPR). To increase efficacy of precordial compressions, the potent vasoconstrict...
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Abstract 418: Mineralocorticoid Receptor in Nucleus of the Solitary Tract Contributes to Aldosterone Stimulation of Salt Intake
A group of neurons in the nucleus of the solitary tract (NTS) contains the mineralocorticoid receptor (MR) which makes these neurons candidates for stimulating salt intake in response to aldosterone.Expand
Novel Split Chest Tube Improves Post-Surgical Thoracic Drainage
Objective Conventional, separate mediastinal and pleural tubes are often inefficient at draining thoracic effusions. Description We developed a Y-shaped chest tube with split ends that divide withinExpand