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BACKGROUND Electroconvulsive therapy (ECT) elicits a rapid and robust clinical response in patients with refractory depression. Neuroimaging measurements of structural plasticity relating to and predictive of ECT response may point to the mechanisms underlying rapid antidepressant effects and establish biomarkers to inform other treatments. Here, we(More)
Introduction Major depressive disorder (MDD) has a high prevalence among psychiatric disorders, with occurrence rates between 4%-14% across the US adult population [1]. Electroconvulsive therapy (ECT) is an effective and rapidly acting treatment for patients with severe depression who fail to respond to antidepressants or psychotherapy. Growing evidence(More)
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