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When monkeys make wrist movements in response to vibration of their hands, primary somatosensory (SI) cortical neurons that adapt quickly to the vibratory stimulus often exhibit two temporally separate types of activity. Initially, these neurons respond to the stimulus. They then cease discharging, only to resume firing prior to the movement. This(More)
The prevalence of homozygous hereditary hemochromatosis (HHC) is estimated at 1:250 in Caucasian adults. Little is known about ethnic subpopulations that might be at increased risk for this disease. HLA data have suggested a Celtic origin for HHC. Screening for HHC was offered to all employees of the Massachusetts Polaroid Corporation. Participants with a(More)
RhoA, a member of the Rho small G protein family, mediates multiple intracellular signaling pathways, and is highly expressed in renal cortex. RhoA translocation is associated with RhoA activation. This study was undertaken to examine the relation of translocation of RhoA in the renal cortex with diabetic renal injury in streptozotocin (STZ)-induced(More)
This study evaluated the effects of vitamin E (alpha-tocopherol) on oxidative DNA damage in a randomized double-blind Phase II chemoprevention trial. Oxidative DNA damage was measured by the level of auto-antibody (Ab) against 5-hydroxymethyl-2'-deoxyuridine (HMdU) in plasma. After the baseline screening, eligible subjects (n = 31; plasma samples from 28(More)
OBJECTIVES To clarify the serological identity of the prototype strain of a group of Actinobacillus pleuropneumoniae isolates that could not be serotyped in previous studies and to establish the serovar of 378 isolates of A pleuropneumoniae obtained from pigs in Australia over the period 1993 to 1996. DESIGN After initial validation, QGD and IHA tests(More)
OBJECTIVE To use the technique of ribotyping to investigate the genetic diversity of Australian isolates of Pasteurella multocida associated with outbreaks of clinical disease in Australian pigs. DESIGN One hundred and seven porcine P multocida isolates were analysed by ribotyping using the restriction enzymes HpaII and HindIII. The genetic population(More)
OBJECTIVE The purpose of this study was to examine the effects of falling history and aging on the latency and magnitude of long latency responses in the lateral gastrocnemius (LG) and tibialis anterior (TA) muscles of older adults. DESIGN Single observation study. SETTING Emory University School of Medicine, Center for Rehabilitation Medicine, serving(More)
Further studies confirm the authors' previous contention that patients suffering from the post-traumatic syndrome (PTS) do recover from this syndrome and return to full-time work before litigation is settled. Failure to have returned to work by the time of settlement indicates a bad prognosis, and such patients rarely return to work afterwards; the older(More)