Bradley J. Segura B.S.

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Acetylcholine release from cholinergic neurons regulates pancreatic exocrine function through pathways that are still under investigation. Pancreatic AR42J acinar cells were studied to determine intracellular calcium ([Ca2+],) release, enzyme activation, and gene expression in response to the acetylcholine analog carbachol (CCh). CCh stimulated(More)
Pancreatic exocrine function has been demonstrated to be under neuronal regulation. The pathways responsible forthis effect, and the long-term consequences of such interactions, are incompletely described. The effects of neuronal depolarization on pancreatic acinar cells were studied to determine whether calcium signaling and c-fos expression were(More)
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