Bradley G. Goodyear

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Although the cerebral cortex has been implicated in the control of swallowing, the functional organization of the human cortical swallowing representation has not been fully documented. Therefore, the present study determined the cortical representation of swallowing in fourteen healthy right-handed female subjects using single-event-related functional(More)
Using multislice segmented echoplanar imaging at 4 T, we have measured an upper bound to the cortical vasculature point-spread function (PSF) using functional magnetic resonance imaging (fMRI) in humans. Our experiments demonstrate that cortical subunits that are approximately 700 microm apart can be resolved using the early part of the hyperoxygenation(More)
We have used high spatial resolution (0.55 mm x 0.55 mm) functional magnetic resonance imaging (fMRI) to show that when stimulus duration is brief (<6 sec), the hyperoxic hemodynamic response to neural activity can resolve the columnar architecture of ocular dominance within the primary visual cortex of humans. Our fMRI maps of ocular dominance columns are(More)
BACKGROUND Previous studies using functional magnetic resonance imaging (fMRI) have identified differential brain activity in healthy subjects performing gambling tasks and in pathological gambling (PG) subjects when exposed to motivational and emotional predecessors for gambling as well as during gambling or response inhibition tasks. The goal of the(More)
Some concepts have richer semantic representations than others. That is, when considering the meaning of concepts, subjects generate more information (more features, more associates) for some concepts than for others. This variability in semantic richness influences responses in speeded tasks that involve semantic processing, such as lexical decision and(More)
BACKGROUND Functional magnetic resonance imaging (fMRI) of motor impairment after stroke strongly depends on patient effort and capacity to make a movement. Hence fMRI has had limited use in clinical management. Alternatively, resting-state fMRI (ie, with no task) can elucidate the brain's functional connections by determining temporal synchrony between(More)
In some contexts, concrete words (CARROT) are recognized and remembered more readily than abstract words (TRUTH). This concreteness effect has historically been explained by two theories of semantic representation: dual-coding [Paivio, A. Dual coding theory: Retrospect and current status. Canadian Journal of Psychology, 45, 255-287, 1991] and(More)
Auditory functional magnetic resonance imaging (fMRI) studies are limited by the presence of noise produced by echo planar imaging (EPI). The current study quantifies the effect of MR scanner noise on psychophysical measures of the perception of loudness and on measures of tonotopy, the representation of auditory frequencies within the auditory cortex.(More)
Many models of word recognition predict a lexical ambiguity disadvantage in semantic categorization tasks (SCTs). However, recent evidence suggests that an ambiguity disadvantage in SCT results from a bias in the decision-making phase of the task and not in the meaning-activation phase: Behavioral effects of ambiguity disappear when these decision biases(More)
OBJECTIVES We used functional MRI (fMRI), transcranial Doppler ultrasound, and visual evoked potentials (VEPs) to determine the nature of blood flow responses to functional brain activity and carbon dioxide (CO2) inhalation in patients with cerebral amyloid angiopathy (CAA), and their association with markers of CAA severity. METHODS In a cross-sectional(More)