Bradley Davidson

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Repetitive or overuse disorders of the lumbar spine affect the lives of workers and athletes. We hypothesize that repetitive anterior lumbar flexion–extension under low or high load will result in significantly elevated pro-inflammatory cytokines expression several hours post-activity. High loads will exhibit significantly higher expression than low loads.(More)
Aldehyde dehydrogenases (ALDHs) catabolize toxic aldehydes and process the vitamin A-derived retinaldehyde into retinoic acid (RA), a small diffusible molecule and a pivotal chordate morphogen. In this study, we combine phylogenetic, structural, genomic, and developmental gene expression analyses to examine the evolutionary origins of ALDH substrate(More)
This paper presents an approach for measuring and monitoring human body joint angles using inertial measurement unit (IMU) sensors. This type of monitoring is beneficial for therapists and physicians because it facilitates remote assessment of patient activities. In our approach, two IMUs are mounted on the upper leg and the lower leg to measure the Euler(More)
The motor control system may compensate for lumbar instability following cyclic work with differential response to load magnitude. In vivo felines were exposed to a cumulative 1 h of cyclic work at 0.25 Hz. One group exposed to light whereas the second to heavy load while recording lumbar displacement and multifidus EMG during work and in single test cycles(More)
BACKGROUND The impact of six sequential static loading and rest of the lumbar spine on the changes in the neuromuscular neutral zones and thereby on spine stability was assessed. METHODS Six 10 min sessions of static load of a moderate level each spaced by 10 min rest were applied to the in vivo feline model. Test cycles of 0.25 Hz and at the same(More)
BACKGROUND Athletic trainers and physical therapists often progress patients through rehabilitation by selecting plyometric exercises of increasing intensity in preparation for return to sport. The purpose of this study was to quantify the intensity of seven plyometric movements commonly used in lower-extremity rehabilitation by joint-specific peak power(More)
Uncertainty that arises from measurement error and parameter estimation can significantly affect the interpretation of musculoskeletal simulations; however, these effects are rarely addressed. The objective of this study was to develop an open-source probabilistic musculoskeletal modeling framework to assess how measurement error and parameter uncertainty(More)
BACKGROUND Cumulative trauma disorder is commonly reported by workers engaged in prolonged repetitive/cyclic occupational activities. Recent experimental evidence confirms that relatively short periods of cyclic lumbar flexion at high loads result in substantial creep of viscoelastic tissues, prolonged periods of its recovery to baseline together with a(More)
Falls are one of the greatest threats to elderly health as they carry out their daily living routines and activities. Therefore, it is very important to detect falls of an elderly in a timely and accurate manner, so that immediate response and proper care can be rendered. Radar is an effective non-intrusive sensing modality which is well suited for this(More)
OBJECTIVES The purposes of this study included the following: (1) to predict L3 contact force during side-lying lumbar manipulation by combining direct and indirect measurements into a single mathematical framework and (2) to assess the accuracy and confidence of predicting L3 contact force using common least squares (CLS) and weighted least squares (WLS)(More)