Bradlee A. Jenkins

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Respiratory failure due to an exacerbation of chronic obstructive airways disease is often seen by clinicians. A case in which respiratory failure was further complicated by acute hypophosphataemia is reported. Replacement phosphate therapy resulted in a dramatic improvement in the clinical condition of the patient. The aetiology of the hypophosphataemia(More)
Morgan et al. (1) concluded that cystic fibrosis (CF) in children and adolescents with a high baseline forced expiratory volume (FEV1) were less likely to have a therapeutic intervention or slower rate of FEV1 decline after a single acute decline in FEV1 of 10%. This conclusion is not well supported due to the arbitrary criteria used for defining a(More)
A recent study by Leonard, Lebecque, Dingemanse, and Leal [1] tested the effect of Miglustat, an alpha inhibitor on the cystic fibrosis conductance regulator gene using total chloride secretion in the nasal epithelium as the key variable estimated from basal nasal potential differences. The conclusion was drawn that “There was no evidence of a treatment(More)
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