Bradford Ramsay

Learn More
The perinatal data of 550 fetuses with a nuchal cord at delivery were compared with those of a control group matched for gestational age, maternal age, and parity. The study group was subsequently subdivided into those fetuses with either single or multiple coils of nuchal cord. No significant differences were found in the comparison of routine ultrasound(More)
OBJECTIVE To study the changes in nitric oxide synthase activities in human myometrium and trophoblast throughout pregnancy and around delivery. METHODS Samples of villous trophoblast were collected from women undergoing elective cesarean delivery at term (n = 12) or voluntary termination of pregnancy in the first (n = 27) or second (n = 11) trimesters of(More)
OBJECTIVE The aim of the study was to establish the incidence of abnormal placental ultrasonographic findings in an unselected obstetric population and determine the usefulness of simple measurements of placental size. In addition, the relationship between these findings, uterine artery Doppler measurements, maternal serum alpha-fetoprotein levels, and(More)
OBJECTIVE To evaluate the relation between the development of the uteroplacental circulation as assessed by Doppler velocimetry and the maternal blood relaxin concentration. METHODS Transvaginal color Doppler investigation of the uteroplacental circulation was performed in 42 healthy women at 6-15 weeks' gestation before termination of pregnancy for(More)
13 women admitted consecutively in preterm labour were recruited to an observational study of the effect of glyceryl trinitrate (GTN) patches on uterine contractions and prolongation of pregnancy. All twenty episodes of preterm labour (at 23-33 weeks' gestation) responded. 1 patient delivered because of cervical incompetence despite cessation of uterine(More)
To evaluate the variations and potential clinical use of serial maternal alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) in pregnancies at risk of pregnancy-induced hypertension (PIH) and/or intrauterine growth retardation (IUGR), we investigated the relationship between placental sonographic findings, uterine artery Doppler measurements, and(More)
Nitric oxide (NO) is a potent vasodilator and inhibitor of platelet aggregation. At present the clinical use of NO donors as inhibitors of platelet activation is limited by their concomitant hypotensive effect. The new NO donor S-nitroso-glutathione (GSNO) has a significant antiplatelet effect at doses that cause only a small decrease in blood pressure in(More)
Homogenates of first (10.1 +/- 1.0 weeks) and third trimester placental villi were analysed for free amino acid concentrations. As has been previously reported, several amino acids showed increased concentrations during early pregnancy when compared to term. In addition, marked differences were seen in the levels of ethanolamine (which was increased(More)