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Many theoretical bond pricing models predict that the credit yield curve facing risky bond issuers is downward-sloping. Previous empirical research ~Sarig and Warga ~1989!, Fons ~1994!! supports these models. Our study examines sets of bonds issued by the same firm with equal priority in the liability structure, but with different maturities, thus holding(More)
Using fragment-based screening of a focused fragment library, 2-aminoquinoline 1 was identified as an initial hit for BACE1. Further SAR development was supported by X-ray structures of BACE1 cocrystallized with various ligands and molecular modeling studies to expedite the discovery of potent compounds. These strategies enabled us to integrate the C-3 side(More)
We survey 384 financial executives and conduct in depth interviews with an additional 23 to determine the factors that drive dividend and share repurchase decisions. Our findings indicate that maintaining the dividend level is on par with investment decisions, while repurchases are made out of the residual cash flow after investment spending. Perceived(More)
Information revelation can occur in a variety of ways. For example, in the home mortgage market, borrowers reveal their expected house tenure through their choice of mortgage contracts. As a result, lenders offer a menu of mortgage interest rate and point combinations in an effort to learn private information about borrowers’ potential mobility. This paper(More)
Significant controversy exists surrounding the hypothesis of consolidation in the real estate industry. Central to the debate is whether REITs can generate economies of scale through asset growth. To date, empirical evidence is limited. For example, Ambrose, Ehrlich, Hughes, and Wachter (2000) find indirect evidence for scale economies but the effect(More)
Current economic volatility has increased the need in industries with limited resources to identify new opportunities to retain its current customer base. Customer retention is one of the key factors to sustain business growth. Developing retention models assist the company by identifying key drivers for increasing retention and focusing the communication(More)
Surface pasteurization for inactivation of Listeria monocytogenes was evaluated for radiant heat prepackage pasteurization, submersed water postpackage pasteurization, and combinations of the two techniques on various types of ready-to-eat deli turkey products obtained from at least four different manufacturers. Products were inoculated either by in-package(More)
Amyloid β-peptide (Aβ) is a key factor in the neurotoxicity of Alzheimer's disease (AD). Recent research has shown that Aβ-mediated neurotoxicity involves free radicals and that Aβ peptides can initiate multiple membrane alterations, including protein oxidation and lipid peroxidation, eventually leading to neuronal cell death. Research also has emphasized(More)
Clostridium histolyticum collagenases ColG and ColH are segmental enzymes that are thought to be activated by Ca(2+)-triggered domain reorientation to cause extensive tissue destruction. The collagenases consist of a collagenase module (s1), a variable number of polycystic kidney disease-like (PKD-like) domains (s2a and s2b in ColH and s2 in ColG) and a(More)
IPO stock prices increased approximately four percent on the first day of secondary market trading over the period 1997 to mid-2004. While these aftermarket returns are accentuated during 1999 and 2000, they persist after the bubble burst. We find this opento-close return is strongly related to adjustments in the offer price relative to the original file(More)
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