Brad H Douglas

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Bovine chromaffin granules and large dense-cored vesicles of bovine splenic nerve were compared by one- and two-dimensional immunoblotting. Both types of vesicles contain chromogranin A, B and C. However, the proteolytic processing of these chromogranins within these vesicles is apparently different. Chromogranin B in chromaffin granules is processed by(More)
The steady-state relationship between mean arterial pressure (AP) and output of sodium and water was determined for one-kidney control (1KC), one-kidney Goldblatt (1KG), normotensive Wistar-Kyoto (WKY), and Okamoto spontaneously hypertensive rats (SHR). Control fluid intake (given by intravenous infusion) was set at approximately 30 ml/day Ringer solution.(More)
Using a postpartum survey, comparing singles to married, we sought to expand existing information on pregnancy occurring among active duty service women. The study instrument was a 59-question survey distributed in the initial 24 hours postpartum and collected prior to discharge. The majority affirmed that pregnancy had not changed career plans. Singles did(More)
caused by salt loading. II: Fluid volume and tissue pressure changes. Am. 1 g64.-Experimental hypertension was produced in dogs by increasing their dietary intake of sodium chloride after removing approximately 707~ of their renal tissue. The changes in mean arterial pressure, interstitial fluid pressure, blood volume, and sodium space were observed during(More)
Opioid peptides including met- and leu-enkephalins are co-stored with catecholamines at similar concentrations in highly purified chromaffin granule fractions from bovine adrenal medulla and large dense cored vesicle (LDV) fractions from bovine splenic nerve. An initial attempt was made to test the universality of the co-storage of enkephalins in LDVs of(More)