Brad Grimm

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A multisystem approach was used to assess the efficiency of several methods for inactivation of Venezuelan equine encephalitis virus (VEEV) vaccine candidates. A combination of diverse assays (plaque, in vitro cytopathology and mouse neurovirulence) was used to verify virus inactivation, along with the use of a specific ELISA to measure retention of VEEV(More)
BACKGROUND After excimer laser photorefractive keratectomy, corneal epithelial and anterior stromal wound healing may produce corneal haze and variability in refractive results among patients and eyes. METHODS We report a retrospective study of 17 selected eyes that received excimer laser photorefractive keratectomy with one of three brands of laser and(More)
—Simulations that require massive amounts of computing power and generate tens of terabytes of data are now part of the daily lives of scientists. Analyzing and visualizing the results of these simulations as they are computed can lead not only to early insights but also to useful knowledge that can be provided as feedback to the simulation, avoiding(More)
Collaboratively monitoring and analyzing large scale simulations from petascale computers is an important area of research and development within the scientific community. This paper addresses these issues when teams of colleagues from different research areas work together to help understand the complex data generated from these simulations. In particular,(More)
PURPOSE Posterior amorphous corneal dysgenesis is a rare disorder previously described in only four families. We expanded the spectrum of findings and updated the classification by adding seven additional cases. METHODS Three index cases were identified during ophthalmic examination at the El Maghraby Eye Hospital and Eye Center in Jeddah, Saudi Arabia.(More)
Between May 25 and July 5, 1986, an epidemic of acute hemorrhagic conjunctivitis affected an estimated 47% of the population on American Samoa. Coxsackievirus A24 variant was isolated from 18 of 22 patients. This is the first documented outbreak of acute hemorrhagic conjunctivitis due to coxsackievirus A24 variant outside of Southeast Asia and the Indian(More)
Managing and understanding the large volumes of scientific data is one of the most difficult challenges scientists face today. As interdisciplinary groups work together, the ability to generate a diversified collection of analyses for a broad audience and in an ad-hoc manner is essential to support effective data exploration. Science portals and Web-based(More)
BACKGROUND Videokeratographic images are important in understanding the corneal topographic changes made by refractive surgery. These images are often poorly presented and cluttered with unnecessary, distracting information. METHODS A simple method for producing better quality keratographic images, using the Computed Anatomy TMS-1 instrument and an(More)
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