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A trend is developing in high performance computing in which commodity processors are coupled to various types of computational accelerators. Such systems are commonly called hybrid systems. In this paper, we describe our experience developing an implementation of the Linpack benchmark for a petascale hybrid system, the LANL Roadrunner cluster built by IBM(More)
A Staphylococcus aureus mutant conditionally defective in DNA ligase was identified by isolation of complementing plasmid clones that encode the S. aureus ligA gene. Orthologues of the putative S. aureus NAD(+)-dependent DNA ligase could be identified in the genomes of Bacillus stearothermophilus and other gram-positive bacteria and confirmed the presence(More)
Commercial database management systems (DBMSs) have historically seen very limited use within the scientific computing community. One reason for this absence is that previous database systems lacked support for the extensible data structures and performance features required within a high-performance computing context. However, database vendors have(More)
InfiniBand is becoming increasingly popular in the area of cluster computing due to its open standard and high performance. I/O interfaces like PCI-express and GX+ are being introduced as next generation technologies to drive InfiniBand with very high throughput. HCAs with throughput of 8x on PCI-express have become available. Recently, support for HCAs(More)
We describe the challenges and opportunities we encountered when developing a hybrid version of the Linpack benchmark for the Los Alamos National Laboratory Roadrunner supercomputing system, which combines traditional x86–64 host processors with IBM PowerXCelle 8i accelerator processors. The challenges included determining the proper division of the host(More)
Commercial database management systems (DBMSs) have historically seen very limited use within the scientific computing community. One reason for this absence is that previous database systems lacked support for the extensible data structures and performance features required within a high-performance computing context. However, database vendors have(More)
Change management for healthcare organizations should be rooted in the following practices: Articulating a business case and vision for change. Assessing organizational risk and readiness. Mobilizing and aligning leaders. Building awareness of and commitment to the change effort. Aligning the organization. Tracking performance improvement and benefit(More)