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Robust pharmacodynamic assay results are valuable for informing go/no-go decisions about continued development of new anti-cancer agents and for identifying combinations of targeted agents, but often… (More)
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA We previously reported the generation of rabbit monoclonal antibodies to twelve EMT (epithelial-to-mesenchymal… (More)
Epithelial-mesenchymal transition (EMT) is a dynamic process whereby epithelial cells acquire mesenchymal properties. Despite the clinical significance of the acquired mesenchymal properties for… (More)
Epithelial-mesenchymal transition (EMT) is a critical process implicated in metastasis. Despite extensive research, the clinical significance of EMT remains unclear, and a quantitative evaluation of… (More)