Bowen Dong

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Antigen-mediated cross-linking of IgE on mast cells triggers a signaling cascade that results in their degranulation and proinflammatory cytokine production, which are key effectors in allergic reactions. We show that the activation of mast cells is negatively regulated by the newly identified adaptor protein Tespa1. Loss of Tespa1 in mouse mast cells led(More)
Combining predictions from multiple sources or models has been shown to be a useful technique in data mining. For example, in network anomaly detection, multiple detectors' output have to be combined to obtain the diagnostic decisions. Unfortunately, as data are generated at an increasingly high speed, existing prediction aggregation methods are facing new(More)
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