Boudewijn Van Damme

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Proprotein convertases are serine endoproteases implicated in the proteolytic processing of a large variety of regulatory proteins. An important role of proprotein convertases in tumorigenic processes has been suggested by various studies. In this study, the role of the proprotein convertase furin in PLAG1 proto-oncogene-induced salivary gland tumorigenesis(More)
H istorically, AA amyloidosis accounts for almost half of the deaths among patients with juvenile chronic arthritis , mainly due to complications of end stage renal failure. 1 Improved survival has been reported in patients whose underlying inflammatory disorder was brought to remission. 2 Tumour necrosis factor (TNFα) blocking agents have been used(More)
Dr. Ylikorkala and colleagues (January 3, p. 42) present evidence for lowered (PGI2) prostacyclin production in normal women after prolonged use of estrogen-containing (OCs) oral contraceptives but not after use of a progestagen-only OC. We have seen a 23-year old multiparous normotensive woman whohad a (HUS) hemolytic uremic syndrome 5 months postpartum(More)
In 1923 Masson described a neo-plastic process consisting of papillary hyperplasia of the vascular endothelial cells, with a consequent obliteration of the vascular lumen, followed by degenerative changes. He introduced the term 'vegetant intravascular hemangioendothelioma'. However, these days it is more commonly known as papillary endothelial hyperplasia(More)
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