Boshao Zhang

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The genetic architecture of schizophrenia is likely contributed by both common and rare variants. 1 Recent genome-wide studies have revealed that common variants in the major histocompatibility complex (MHC) region, TCF4 and other genes are associated with schizophrenia. 1 In addition, rare copy-number variation (CNV) regions in broad regions like 1q21.1,(More)
Genome-wide association studies have successfully identified many common variants associated with complex human diseases. However, a large portion of the remaining heritability cannot be explained by these common variants. Exploring rare variants associated with diseases is now catching more attention. Several methods have been recently proposed for(More)
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