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It is imperative that users of voxel-based morphometry (VBM) be aware of its reproducibility and the factors which influence results. We assessed the reproducibility of a VBM software package (SPM5) in measuring gray matter (GM) and white matter (WM) volumes from at least two consecutive 3D T1-weighted studies in 64 subjects. Factors investigated were the(More)
To date, few studies have examined the functional connectivity of brain regions involved in complex executive function tasks, such as cognitive set-shifting. In this study, eighteen healthy volunteers performed a cognitive set-shifting task modified from the Wisconsin card sort test while undergoing functional magnetic resonance imaging. These modifications(More)
PURPOSE Selective internal radiotherapy (SIRT) with yttrium-90 ((90)Y) resin microspheres can improve the clinical outcomes for selected patients with inoperable liver cancer. This technique involves intra-arterial delivery of β-emitting microspheres into hepatocellular carcinomas or liver metastases while sparing uninvolved structures. Its unique mode of(More)
This paper introduces Set-based Cascading Approach for Medical Image Segmentation (SCAMIS), a new methodology for segmentation of medical imaging by integrating a number of algorithms. Existing approaches typically adopt the pipeline methodology. Although these methods provide promising results, the results generated are still susceptible to(More)
Stem cell transplantation for regenerative medicine has made significant progress in various injury models, with the development of modalities to track stem cell fate and migration post-transplantation being currently pursued rigorously. Magnetic resonance imaging (MRI) allows serial high-resolution in vivo detection of transplanted stem cells labeled with(More)
AIMS Superparamagnetic magnetite nanoparticles have been under intensive investigation in nanomedicine. However, it is still a challenge to synthesize high-quality water-stable magnetite nanoparticles for better magnetic performance and less side effects in medical MRI and nanothermotherapy. MATERIALS & METHODS We successfully synthesized hydrophilic(More)
Poly(poly(ethyleneglycol) monomethacrylate) (P(PEGMA))-grafted magnetic nanoparticles (MNPs) were successfully prepared via a solvent-free atom transfer radical polymerization (ATRP) method. The macroinitiators were immobilized on the surface of 6.4+/-0.8 nm Fe(3)O(4) nanoparticles via effective ligand exchange of oleic acid with 3-chloropropionic acid(More)
Bifunctional superparamagnetic magnetite/poly(dl-lactic acid-co-alpha,beta-malic acid) composite nanoparticles (PLMA-MNPs) detectable by both magnetic resonance imaging (MRI) and fluorescence microscopy were synthesized by coating Fe(3)O(4) nanoparticles with biodegradable poly(dl-lactic acid-co-alpha,beta-malic acid) copolymer (PLMA) with covalently bound(More)