Boris Troyanovsky

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Standard fluorescence microscopy approaches rely on measurements at single excitation and emission bands to identify specific fluorophores and the setting of thresholds to quantify fluorophore intensity. This is often insufficient to reliably resolve and quantify fluorescent labels in tissues due to high autofluorescence. Here we describe the use of(More)
Harmonic and intermodulation distortion effects play an important role in numerous analog applications, particularly in such areas as wireless communication systems. In this paper, we present a two-dimensional harmonic balance semiconductor device simulator which accurately models these nonlinear effects at the physical (drift-diffusion) level. The(More)
Transient production of gamma-retroviruses, including self-inactivating (SIN) retroviruses, is a common method for rapidly generating virus capable of gene delivery. Stable (continuous) production of virus is preferable to transient production for clinical and biotechnology purposes, however, because it allows for significant quantities of a uniform virus(More)
Harmonic and interrnodiilation distortion effects play a key role in the design and siibsequent performance of analog HF/pWave systems. Due to the wide range of frequency components present in such systems, ordinary transient analysis is both extremely time-consuming and insufficiently accurate. In this paper, we present a harmonic balance version of the(More)
SUMMARY As wireless communication is penetrating every corner of the globe, the optimum design and accurate analysis of RF, power semiconductor devices become one of the biggest challenges in EDA and TCAD (Technology CAD) tool development. The performance gauge for these devices is quite different from that for either digital or analog devices aimed at(More)
Minimal piggyBac vectors are a modified single-plasmid version of the classical piggyBac delivery system that can be used for stable transgene integration. These vectors have a truncated terminal domain in the delivery cassette and thus, integrate significantly less flanking transposon DNA into host cell chromatin than classical piggyBac vectors. Herein, we(More)
Historically, analog models and the simulators in which they are embedded form a single analog simulation kernel. This was true of SPICE and its predecessors and is true of most commercial and proprietary analog simulators in use today. As a consequence, while model interfaces generally serve the same function (allowing the model to define the differential(More)
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