Boris Müller

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The aim of this work is to build up a common framework for a class of discriminative training criteria and optimization methods for continuous speech recognition. A uni®ed discriminative criterion based on likelihood ratios of correct and competing models with optional smoothing is presented. The uni®ed criterion leads to particular criteria through the(More)
IntroductIon Image registration, segmentation, and visualization are three major components of medical image processing. Three-dimensional (3D) digital medical images are three dimensionally reconstructed, often with minor artifacts, and with limited spatial resolution and gray scale, unlike common digital pictures. Because of these limitations, image(More)
We introduce a set of integrated interaction techniques to interpret and interrogate dimensionality-reduced data. Projection techniques generally aim to make a high-dimensional information space visible in form of a planar layout. However, the meaning of the resulting data projections can be hard to grasp. It is seldom clear why elements are placed far(More)
Infections with the opisthorchiid liver flukes Clonorchis sinensis, Opisthorchis viverrini, and Opisthorchis felineus cause serious health problems in endemic areas of Southeast Asia and countries of the former Soviet Union. Chronic infections—even with low worm burdens—may lead to the development of fatal cholangiocarcinoma and related symptoms. A more(More)
In the present study, PCR procedures have been established for a rapid and easy preparation of DNA of parasite stages from the intermediate hosts, i.e. sporocysts and rediae in snails and metacercariae in fishes. Primers have been developed, which enable a highly sensitive and species-specific detection of Clonorchis sinensis.
BACKGROUND Intracorporeal suturing and knot tying (ICKT) in minimal invasive surgery (MIS) represents a key skill for advanced procedures. Different methods exist for measuring knot quality and performance, but the heterogeneity of these methods makes direct comparisons difficult. The aim of this study is to compare the quality of a laparoscopic knot to one(More)
PURPOSE To report PSA relapse-free survival and toxicity outcomes of prostate cancer patients who have undergone three-dimensional computer-optimized high-dose-rate (HDR) brachytherapy with external beam radiotherapy as definitive treatment. METHODS AND MATERIALS One hundred five patients consecutively treated between 1998 and 2004 are reported. All(More)
Pharmacokinetic parameters may be influenced by pregnancy and labour. A number of antibiotics and chemotherapeutics were studied by the authors who found reduction of fictitious initial concentration as well as increase of both volume of distribution and total clearance. Elimination half-life was found to be prolonged with significance only in women in(More)
The metabolism of the herbicide glufosinate-ammonium was investigated in heterotrophic cell suspension and callus cultures of transgenic (bar-gene) and non-transgenic sugarbeet (Beta vulgaris). Similar studies were performed with suspensions of carrot (Daucus carota), purple foxglove (Digitalis purpurea) and thorn apple (Datura stramonium). 14C-labelled(More)
In the context of current web and personal information management developments, we argue that facet browsing is an increasingly important interface paradigm. However, current implementations neglect two important aspects of metadata distributions: the relative proportions of metadata occurrences and the unusualness of this proportion compared to a global(More)