Boris B. Kheyfets

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In this work we derive analytically various thermodynamic properties of bolalipid membranes using microscopic model (elastic strings) and path-integral technique. Among calculated characteristics are lateral pressure profile (with and without hairpin bolalipids), chain orientational order parameter, pressure-area isotherms, coefficient of thermal area(More)
Smaller area per molecule in a DPPC-cholesterol multicomponent monolayers than in pure DPPC suggests that DPPC lipids straighten when in contact with cholesterol. Using flexible strings model that imitates entropic repulsion between lipid chains in the membrane, one can reproduce the DPPC-cholesterol area per molecule diagram at a low cholesterol(More)
We consider a model of bilayer lipid membrane with bola-lipids. The bola-lipid is modeled by linking tails of the hydrophobic chains in the opposite monolayers within bilayer as a first approximation. A number of thermodynamical characteristics are calculated analytically and compared with the ones of a regular membrane without chains linkage. Pronounced(More)
Analytical derivation of thermodynamic properties of bilayer membrane with interdigitation. Abstract We consider a model of bilayer lipid membrane with interdigitation, in which the lipid tails of the opposite monolayers interpenetrate. The interdigitation is modeled by linking tails of the hydrophobic chains in the opposite monolayers within bilayer as a(More)
Bending and Gaussian moduli of a homogenious single-component lipid bilayer are calculated analytically using microscopic model of the lipid hydrocarbon chains. The approach allows for thermodynamic averaging over different chains conformations. Each chain is modeled as a flexible string with finite bending rigidity and an incompressible cross-section area.(More)
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