Boqiang Fan

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Odor responses of mitral cells in the olfactory bulb are observed to be sparse spatially and decorrelated in response to odor signals [1]. We have built a large scale biophysical network model of olfactory bulb composed of mitral and granule cells, corresponding to 1/100th of the real system in the rat, and used direct experimental imaging data of glomeruli(More)
There is a growing interest in estimating actual density ranges of Na+ channels in the very thin axon, especially in the action potential (AP) initiation zone, i.e., the axon initial segment (AIS, 20-50 microns away from the cell body). Both immunostaining studies and patch-clamp recordings indicated a relatively high density of Na+ channels in AIS of(More)
Experiments have demonstrated that cortical and sensory neurons prefer to response to signals with characteristics of long-term correlation or 1/f noise feature better than signals with no correlation like white-noise-type [1]. In order to study the underlying mechanism, we built up a cortical neuronal model [2] based on Hodgkin-Huxley theory to study the(More)
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