Bong-Kun Choi

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Pentraxin 3 (PTX3), a modulator of tumor-associated inflammation, is known to be positively correlated with tumor grade and severity of malignancies, but its exact role remains unclear. This study found that PTX3 expression was up-regulated in distant bone metastases of breast cancer compared to lung, liver, and brain metastases in 64 human breast cancer(More)
INTRODUCTION Interleukin-34 (IL-34) is a recently defined cytokine, showing a functional overlap with macrophage colony stimulating factor (M-CSF). This study was undertaken to address the expression of IL-34 in rheumatoid arthritis (RA) patients and to investigate its regulation and pathogenic role in RA. METHODS IL-34 levels were determined in the RA(More)
BACKGROUND CXC chemokine receptor 4 (CXCR4), a member of the G-protein-coupled chemokine receptor family, can serve as a co-receptor along with CD4 for entry into the cell of T-cell tropic X4 human immunodeficiency virus type 1 (HIV-1) strains. Productive infection of T-lymphoblastoid cells by X4 HIV-1 markedly reduces cell-surface expression of CD4, but(More)
The INK4a/ARF locus, which encodes the two distinct proteins p16(INK4a) and p14(ARF), is frequently altered in various hematological malignancies as well as in other types of cancers in humans. In this study, we surveyed tumors that had spontaneously developed in Ink4a/Arf-deficient mice with an inbred FVB/NJ genetic background. We found that an(More)
OBJECTIVE To evaluate the effect of an arm sling on gait speed and energy efficiency of patients with hemiplegia. DESIGN A randomized crossover design. SETTING A rehabilitation department of a university hospital. SUBJECTS Thirty-seven outpatients with hemiplegia were included in this study. INTERVENTIONS All patients walked on a 20-m walkway twice(More)
BACKGROUND HIV-1 mediated perturbation of the plasma membrane can produce an alteration in the transmembrane gradients of cations and other small molecules leading to cell death. Several HIV-1 proteins have been shown to perturb membrane permeability and ion transport. Xenopus laevis oocytes have few functional endogenous ion channels, and have proven(More)
Abbreviations: CKAP2/TMAP, cytoskeletal associated protein 2/tumor-associated microtubule associated protein; DD-PCR, differential-display polymerase chain reaction; DLC-1, deleted in liver cancer-1; HIP/PAP, hepatocarcinoma-intestine-pancreas/ pancreatitis-associated protein; REG3A, regenerating islet-derived 3 alpha Abstract Gastric carcinoma is(More)
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