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- Publications
- Influence
Antimicrobial Peptides for Therapeutic Applications: A Review
- M. Seo, H. Won, J. Kim, Tsogbadrakh Mishig-Ochir, Bong-Jin Lee
- Biology, Medicine
- Molecules
- 1 October 2012
Antimicrobial peptides (AMPs) have been considered as potential therapeutic sources of future antibiotics because of their broad-spectrum activities and different mechanisms of action compared to… Expand
Bax Inhibitor-1 Is a pH-dependent Regulator of Ca2+ Channel Activity in the Endoplasmic Reticulum*
- H. Kim, Geum-Hwa Lee, +10 authors H. Chae
- Biology, Medicine
- Journal of Biological Chemistry
- 6 June 2008
In this study, Bax inhibitor-1 (BI-1) overexpression reduces the ER pool of Ca2+ released by thapsigargin. Cells overexpressing BI-1 also showed lower intracellular Ca2+ release induced by the Ca2+… Expand
Antimicrobial peptides: therapeutic potentials
- S. Kang, Sung Jean Park, Tsogbadrakh Mishig-Ochir, Bong-Jin Lee
- Medicine
- Expert review of anti-infective therapy
- 9 November 2014
The increasing appearance of multidrug-resistant pathogens has created an urgent need for suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as defensive weapons… Expand
In defence of metric learning for speaker recognition
- Joon Son Chung, Jaesung Huh, +7 authors Icksang Han
- Computer Science, Engineering
- INTERSPEECH
- 26 March 2020
TLDR
Structural overview on the allosteric activation of cyclic AMP receptor protein.
- H. Won, Yoo-Sup Lee, S. Lee, Bong-Jin Lee
- Biology, Medicine
- Biochimica et biophysica acta
- 1 September 2009
Cyclic AMP receptor protein (CRP) is a prokaryotic global transcription regulator that controls the expression of nearly 200 genes. The protein, allosterically activated by cAMP binding, binds to DNA… Expand
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells
Summary Transmembrane 4 L six family member 5 (TM4SF5) plays an important role in cell migration, and focal adhesion kinase (FAK) activity is essential for homeostatic and pathological migration of… Expand
Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
- In-Gyun Lee, S. J. Lee, Susanna Chae, K. Lee, J. Kim, Bong-Jin Lee
- Biology, Medicine
- Nucleic acids research
- 6 July 2015
Toxin-antitoxin (TA) systems play important roles in bacterial physiology, such as multidrug tolerance, biofilm formation, and arrest of cellular growth under stress conditions. To develop novel… Expand
Functional Identification of Toxin-Antitoxin Molecules from Helicobacter pylori 26695 and Structural Elucidation of the Molecular Interactions*
- Kyung-Doo Han, A. Matsuura, +7 authors Bong-Jin Lee
- Biology, Medicine
- The Journal of Biological Chemistry
- 1 December 2010
Bacterial toxin-antitoxin (TA) systems are associated with many important cellular processes including antibiotic resistance and microorganism virulence. Here, we identify and structurally… Expand
Action mechanism and structural requirements of the antimicrobial peptides, gaegurins.
- H. Won, S. Kang, Bong-Jin Lee
- Biology, Medicine
- Biochimica et biophysica acta
- 1 August 2009
Gaegurins (GGNs) are a family of cationic, alpha-helical, antimicrobial peptides that were isolated from a Korean frog, Glandirana emeljanovi (formerly classified as Rana rugosa) and represent one of… Expand
Structure, Biology, and Therapeutic Application of Toxin–Antitoxin Systems in Pathogenic Bacteria
- K. Lee, Bong-Jin Lee
- Biology, Medicine
- Toxins
- 1 October 2016
Bacterial toxin–antitoxin (TA) systems have received increasing attention for their diverse identities, structures, and functional implications in cell cycle arrest and survival against environmental… Expand
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