Bojan Musizza

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We hypothesized that, associated with the state of anaesthesia, characteristic changes exist in both cardio-respiratory and cerebral oscillator parameters and couplings, perhaps varying with depth of anaesthesia. Electrocardiograms (ECGs), respiration and electroencephalograms (EEGs) were recorded from two groups of 10 rats during the entire course of(More)
One of the current challenges in medicine is monitoring the patients' depth of general anaesthesia (DGA). Accurate assessment of the depth of anaesthesia contributes to tailoring drug administration to the individual patient, thus preventing awareness or excessive anaesthetic depth and improving patients' outcomes. In the past decade, there has been a(More)
Previous analyses of cardiorespiratory coupling in anaesthesia have used linear methods. 1 A different approach based on wavelet transform 2 and synchronization indices revealed a marked increase in synchronization between the rhythmic oscillations of respiration and the ECG 3 in rats given ketamine and xylazine. The direction of interaction also changed(More)
Cold-induced vasodilatation (CIVD) is proposed to be a protective response to prevent cold injuries in the extremities during cold exposure, but the laboratory-based trainability of CIVD responses in the hand remains equivocal. Therefore, we investigated the thermal response across the fingers with repeated local cold exposure of the whole hand, along with(More)
One problem evaluating mobile and wearable devices is that they are used in mobile settings, making it hard to collect usability data. We present a study of tap-based selection of on-screen targets whilst walking and sitting, using a PocketPC instrumented with an accelerometer to collect information about user activity at the time of each tap. From these(More)
Conversation partners on mobile phones can align their walking gait without physical proximity or visual feedback. We investigate gait synchronization, measured by accelerometers while users converse via mobile phones. Hilbert transforms are used to infer gait phase angle, and techniques from synchronization theory are used to infer level of alignment.(More)
abstract Instrumented usability analysis involves the use of sensors during a usability study which provide observations from which the evaluator can infer details of the context of use, specific activities, or disturbances. This is particularly useful for the evaluation of mobile and wearable devices which are currently difficult to test realistically(More)
Depth of anaesthesia monitors usually analyse cerebral function with or without other physiological signals; non-invasive monitoring of the measured cardiorespiratory signals alone would offer a simple, practical alternative. We aimed to investigate whether such signals, analysed with novel, non-linear dynamic methods, would distinguish between the awake(More)
We investigated the hypothesis that during tonic pain stimulus, neurovascular coupling (NVC) decreases, measuring visually evoked cerebral blood flow velocity response (VEFR) during cold pressor test (CPT) in healthy human subjects as a test. VEFR was calculated as a relative increase in blood flow velocity in the posterior cerebral artery from average(More)
Cold-induced vasodilatation (CIVD) is a cyclical increase in finger temperature that has been suggested to provide cryoprotective function during cold exposures. Physical fitness has been suggested as a potential factor that could affect CIVD response, possibly via central (increased cardiac output, decreased sympathetic nerve activity) and/or peripheral(More)