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Membrane ruffles in cell migration: indicators of inefficient lamellipodia adhesion and compartments of actin filament reorganization.

• Bodo Borm, Robert Pascal Requardt, Volker Herzog, Gregor Kirfel
• Experimental cell research
• 2005

During epithelial cell migration, membrane ruffles can be visualized by phase contrast microscopy as dark waves arising at the leading edge of lamellipodia that move centripetally toward the main… (More)

Cell migration: mechanisms of rear detachment and the formation of migration tracks.

• Gregor Kirfel, Alexander Rigort, Bodo Borm, Volker Herzog
• European journal of cell biology
• 2004

Cell migration is central to many biological and pathological processes, including embryogenesis, tissue repair and regeneration as well as cancer and the inflammatory response. In general, cell… (More)

One step ahead: role of filopodia in adhesion formation during cell migration of keratinocytes.

• Claudia Schäfer, Bodo Borm, Simone Born, Christoph Möhl, Eva-Maria Eibl, Bernd Hoffmann
• Experimental cell research
• 2009

Cell adhesion is an essential prerequisite for cell function and movement. It depends strongly on focal adhesion complexes connecting the extracellular matrix to the actin cytoskeleton. Especially in… (More)

Laminin-5-deficient human keratinocytes: defective adhesion results in a saltatory and inefficient mode of migration.

• Benedikt Hartwig, Bodo Borm, Holm Schneider, Meral Julia Arin, Gregor Kirfel, Volker Herzog
• Experimental cell research
• 2007

Laminin-5 is a major adhesion protein of the skin basement membrane and crucially involved in integrin-mediated cell substrate attachment of keratinocytes, which is important for hemidesmosomal… (More)

The secretory beta-amyloid precursor protein is a motogen for human epidermal keratinocytes.

• Gregor Kirfel, Bodo Borm, Alexander Rigort, Volker Herzog
• European journal of cell biology
• 2002

Cell migration is known to be triggered by constituents of the extracellular matrix such as fibronectin and by soluble mediators commonly summarized as motogens. Many growth factors such as the… (More)

CD83 localization in a recycling compartment of immature human monocyte-derived dendritic cells.

• Elisabeth Klein, Susanne Koch, +4 authors Thomas Bieber
• International immunology
• 2005

Dendritic cells (DC) change their phenotype and functional properties during maturation. CD83 cell surface expression is induced on mature DC (mDC). In this study, we investigated intracellular CD83… (More)

Structural and compositional analysis of the keratinocyte migration track.

• Gregor Kirfel, Alexander Rigort, Bodo Borm, Carsten Schulte, Volker Herzog
• Cell motility and the cytoskeleton
• 2003

Slowly migrating cells such as fibroblasts leave behind a "migration track," which has been assumed not to occur in fast-moving cells such as keratinocytes. Here we show that keratinocytes left… (More)

CD 83 localization in a recycling compartment of immature human monocyte-derived dendritic cells

• Elisabeth Klein, Susanne Koch, +4 authors Thomas Bieber
• 2005

Dendritic cells (DC) change their phenotype and functional properties during maturation. CD83 cell surface expression is induced on mature DC (mDC). In this study, we investigated intracellular CD83… (More)

John von Neumann Institute for Computing Role of Filopodia in Adhesion Formation During Migration of Epithelial Cells

• Bodo Borm, Sabine Born, Rudolf Merkel, Bert Hoffmann, Sandipan Mohanty, Olav Zimmermann
• 2007

c © 2007 by John von Neumann Institute for Computing Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made… (More)

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