Bobby Heydari

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BACKGROUND Animal studies have shown that neuroactive steroids modulate the activity of the gamma-aminobutyric acid type A/benzodiazepine receptor complex and that these steroids display anxiolytic or anxiogenic activity depending on their positive (e.g. allopregnanolone) or negative allosteric modulation (e.g. dehydroepiandrosterone sulphate) of this(More)
PURPOSE To evaluate the feasibility of accelerated cardiac MR (CMR) perfusion with radial sampling using nonlinear image reconstruction after exercise on an MR-compatible supine bike ergometer. METHODS Eight healthy subjects were scanned on two separate days using radial and Cartesian CMR perfusion sequences in rest and exercise stress perfusion. Four(More)
Objective The relationship of infarction heterogeneity with indices of ventricular remodeling quantified during the convalescent phase of acute infarct healing is unknown. We hypothesize that a dynamic increase of the proportion of infarct core relative to peri-infarct zone (PIZ) following acute myocardial infarction (MI) may be associated with adverse(More)
Characterization of subacute and convalescent fibrotic burden in the remote myocardium after acute infarction provides strong and incremental prediction of changes in left and right functions and final infarct size, incremental to knowledge of the subacute infarct size Summary To test the hypothesis that fibrotic burden in remote myocardium quantified by(More)