Bobby Heydari

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BACKGROUND Animal studies have shown that neuroactive steroids modulate the activity of the gamma-aminobutyric acid type A/benzodiazepine receptor complex and that these steroids display anxiolytic or anxiogenic activity depending on their positive (e.g. allopregnanolone) or negative allosteric modulation (e.g. dehydroepiandrosterone sulphate) of this(More)
PURPOSE To evaluate the feasibility of accelerated cardiac MR (CMR) perfusion with radial sampling using nonlinear image reconstruction after exercise on an MR-compatible supine bike ergometer. METHODS Eight healthy subjects were scanned on two separate days using radial and Cartesian CMR perfusion sequences in rest and exercise stress perfusion. Four(More)
Infarct tissue heterogeneity by contrast-enhanced MRI is a novel predictor of mortality in patients with coronary artery disease with reduced left ventricular systolic function
OBJECTIVES This study assessed whether impaired fasting glucose (IFG), insulin resistance, and waist-to-hip ratio (WHR) had effects on cardiac remodeling, independent of obesity, in the MESA (Multi-Ethnic Study of Atherosclerosis) trial. BACKGROUND Recent studies have suggested that central obesity and insulin resistance may be primary mediators of(More)
Characterization of subacute and convalescent fibrotic burden in the remote myocardium after acute infarction provides strong and incremental prediction of changes in left and right functions and final infarct size, incremental to knowledge of the subacute infarct size Summary To test the hypothesis that fibrotic burden in remote myocardium quantified by(More)
Objective The relationship of infarction heterogeneity with indices of ventricular remodeling quantified during the convalescent phase of acute infarct healing is unknown. We hypothesize that a dynamic increase of the proportion of infarct core relative to peri-infarct zone (PIZ) following acute myocardial infarction (MI) may be associated with adverse(More)