Bob Wray

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Four mouse monoclonal antibodies (mabs) were shown by immunoblotting procedures to recognize the major, basic, membrane-bound Mr 43,000 protein (43K protein) of acetylcholine receptor-rich postsynaptic membranes from Torpedo nobiliana . These mabs and a mab against an extracellular determinant on the acetylcholine receptor were used to localize the two(More)
Simulation-based training offers the potential for relatively low-cost training available at any time and almost any duty station. However, a main drawback of simulation-based training is the lack of oversight in the training process. Simulations often depend on a fixed number of pre-defined training scenarios that are designed to test training objectives(More)
(the Soar-RL Tutorial is currently a separate document from this six-part tutorial) Soar Tutorial 2 Acknowledgments This tutorial is the culmination of work by many people, and has been refined and expanded significantly over several years. Soar 8, based on Bob Wray's thesis work with contributions from Randy Jones and Mike vanLent, was a significant(More)
There is no clear picture of the critical events that lead to the transition from reversible to irreversible injury. Many studies have suggested that a rise in cytosolic free Ca2+ initiates plasma membrane bleb formation and a sequence of events that lead ultimately to cell death. In recent studies, we have measured changes in cytosolic free Ca2+,(More)
Two monoclonal antibodies (mabs) previously prepared against Torpedo acetylcholine receptor are shown to recognize a synthetic nonadecapeptide corresponding to lys360-glu377 of the gamma subunit. The reaction was demonstrated by solid-phase enzyme-linked immunoabsorbent assays, by inhibition of binding of the mabs to receptor, and by immunoprecipitation of(More)
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