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OBJECTIVES To analyze aquaporin-4 (AQP4) antibody-positive patients who do not fulfill the current diagnostic criteria of neuromyelitis optica (NMO) and NMO spectrum disorders (NMOSD). METHODS We used a cell-based assay (CBA) with AQP4-transfected cells to detect AQP4 antibody in 298 consecutive patients with inflammatory CNS disorders seen at Tohoku(More)
The vicinity of an ancient abandoned copper mine located on the Isle of Anglesey was assessed for the dispersion of copper, zinc, lead, and cadmium into the surrounding environment. Extraction of soil, lichens, cattle feces, and Calluna vulgaris L. (ling) tissue, using aqua regia, was carried out and together with water samples, these were analyzed using(More)
This research addresses the occurrence, detection and possible fate of tungsten in the vicinity of an abandoned mine in the English Lake District. Aqua regia extraction and subsequent analysis of spoil and vegetation confirmed the presence of tungsten and other heavy metals. Spoil samples examined were last worked almost 100 years ago and the concentrations(More)
Aspects of the bioaccumulation of heavy metals are reviewed and possible evidence of homeostasis is highlighted. Examination and analysis of olive (Olea europaea L.) trees growing in close proximity to a copper dominated spoil tip dating from at least 2000 years BP, on the island of Cyprus, revealed both bioaccumulation and partitioning of copper, lead and(More)
The mobility and bioavailability of tungsten and associated metals are examined in calcareous soils and subsequent bioaccumulation by four species of plants is determined. Apparent bioavailability of metalliferous cations indicated by accepted monitoring methods and actual bioaccumulation is compared using regression analysis. Two soil extraction procedures(More)
Britannia Mine in British Columbia, Canada, is a major source of copper and other heavy metal pollutants, which enter the sea at Howe Sound. This investigation aims to determine whether there is sufficient Cd, Cu, Pb, and Zn, in the terrestrial environment surrounding the mine to suggest that dispersion and subsequent bioaccumulation has occurred in the(More)
This initial research examined the presence, distribution and bioavailability of Cu, Cr, Ni, Mn and Fe in a wetland area of southern Guam. The research sites are within an area covered with saporite, a soil type derived from volcanic deposits on the island. Leaf tissue of Pandanus tectorius was extracted and analysed to determine the bioaccumulation of the(More)
Optically variable pigment technologies for markings and inks have increased in use as overt protection methods for document and product security. These technologies use optical reflective effects including interference technologies that create angular dependent color changes. Novel developments in different inorganic and organic pigments offer potentially(More)
Given the initial position and velocity of an object, such as a satellite in orbit around the Earth, it is possible to determine its position and velocity at any other time by integrating the equations of motion. This prediction method is called propagating. Specifying the position and velocity of the satellite at a specific time, called the epoch, is a(More)