Bo Zhuang

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BACKGROUND Pancreatic carcinoma possesses one of the highest lethality rates, highest drug-resistance, and highest incidence rates. The objective of this research was to enhance the efficacy and drug-resistance for pancreatic carcinoma by using inhibition of SIRT1 combined with gemcitabine therapy methods. METHODS Three pancreatic carcinoma cells (PANC-1(More)
Chemoresistance is the major impediment for treating pancreatic cancer. Herb-derived compound triptolide (TP) can inhibit proliferation of chemo-resistant pancreatic cancer (CPC) cell lines through multiple mechanisms, which exhibited superior anticancer efficacy compared with gemcitabine. However, toxicity due to non-specific exposure to healthy tissues(More)
PURPOSE In recent years, fusion of multi-parametric MRI (mp-MRI) with transrectal ultrasound (TRUS)-guided biopsy has enabled targeted prostate biopsy with improved cancer yield. Target identification is solely based on information from mp-MRI, which is subsequently transferred to the subject coordinates through an image registration approach. mp-MRI has(More)
Real-time 3-D ultrasound scan conversion (SC) in software has not been practical due to its high computation and I/O data handling requirements. In this paper, we describe software-based 3-D SC with high volume rates using a multicore processor, Cell. We have implemented both 3-D SC approaches: 1) the separable 3-D SC where two 2-D coordinate(More)
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