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Ischemia/reperfusion (I/R) injury is a common cause of injury to target organs such as brain, heart, and kidneys. Renal injury from I/R, which may occur in renal transplantation, surgery, trauma, or sepsis, is known to be an important cause of acute kidney injury. The detailed molecular mechanism of renal I/R injury is still not fully clear. Here, we(More)
Renal ischemia/reperfusion (I/R) is a major cause of acute renal failure. Quercetin, a flavonoid antioxidant, presents in many kinds of food. The molecular mechanism of quercetin on renal protection during I/R is still unclear. Here, we investigated the role of AMP-activated protein kinase (AMPK)-regulated autophagy in renal protection by quercetin. To(More)
Low-intensity pulsed ultrasound (LIPUS) stimulation has been shown to increase the expression of brain-derived neurotrophic factor (BDNF) in astrocytes of an in vitro model and rat brains of an in vivo model; however, their molecular mechanisms are still not well clarified. Here, we investigated the underlying mechanisms of BDNF enhancement by LIPUS in rat(More)
The proposed humanoid robot (HR) with a stereo vision system (SVS) captures a sequence of 3-D motion images of a human, which is faced to the proposed HR. After the inquiry of enough motion sequences, the motion detection via image ratio and background registration, the estimation of five feature points (i.e., head, four tips of two arms and legs) of human(More)
One of the main technologies of cloud computing is virtualization. Virtualization allows Virtual Machines (VMs) to share physical resources simultaneously resulting in higher utilization of hardware resources and lower infrastructure costs. With the proliferation of VMs, the importance of virtual switches (vSwitches) comes to the forefront. The concept of(More)
Experimental approaches to identify drug-target interactions (DTIs) among a large number of chemical compounds and proteins are still costly and time-consuming. As an assistant, computational approaches are able to rapidly infer potential drug or target candidates for diverse screenings in a large scale. The most difficult scenario (S4) of screenings tries(More)
AIM To investigate the pathophysiological role of C/EBP homologous protein (CHOP) in severe acute pancreatitis and associated lung injury. METHODS A severe acute pancreatitis model was induced with 6 injections of cerulein (Cn, 50 μg/kg) at 1-h intervals, then intraperitoneal injection of lipopolysaccharide (LPS, 7.5 mg/kg) in CHOP-deficient (Chop(-/-))(More)
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