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PURPOSE Recent increases in incidence and survival of oropharyngeal cancers in the United States have been attributed to human papillomavirus (HPV) infection, but empirical evidence is lacking. PATIENTS AND METHODS HPV status was determined for all 271 oropharyngeal cancers (1984-2004) collected by the three population-based cancer registries in the(More)
Studies of nitric oxide over the past two decades have highlighted the fundamental importance of gaseous signaling molecules in biology and medicine. The physiological role of other gases such as carbon monoxide and hydrogen sulfide (H2S) is now receiving increasing attention. Here we show that H2S is physiologically generated by cystathionine gamma-lyase(More)
Regression testing assures changed programs against unintended amendments. Rearranging the execution order of test cases is a key idea to improve their effectiveness. Paradoxically, many test case prioritization techniques resolve tie cases using the random selection approach, and yet random ordering of test cases has been considered as ineffective.(More)
Intended for network-wide dissemination of commands, configurations and code binaries, flooding has been investigated extensively in wireless networks. However, little work has yet been done on low-duty-cycle wireless sensor networks in which nodes stay asleep most of time and wake up asynchronously. In this type of network, a broadcasting packet is rarely(More)
We present the genome sequences of a new clinical isolate of the important human pathogen, Aspergillus fumigatus, A1163, and two closely related but rarely pathogenic species, Neosartorya fischeri NRRL181 and Aspergillus clavatus NRRL1. Comparative genomic analysis of A1163 with the recently sequenced A. fumigatus isolate Af293 has identified core, variable(More)
Principal Component Analysis (PCA) is a widely used to learn a low-dimensional representation. In many applications, both vector data X and graph data W are available. Laplacian embedding is widely used for embedding graph data. We propose a graph-Laplacian PCA (gLPCA) to learn a low dimensional representation of X that incorporates graph structures encoded(More)
This paper describes a low-power Intel Architecture (IA) processor specifically designed for Mobile Internet Devices (MID) and UltraMobile PCs (UMPC) where average power consumed is in the order of a few hundred mW (as measured by MobileMark’05 OP @ 60 nits brightness) with performance similar to mainstream Ultra-Mobile PCs. The design consists of an(More)
AIM To determine the basic demographic features of colorectal cancer (CRC) in five hospitals located in four different areas of Guangdong Province, China. METHODS A review of patient records from 1986 to 2006 from five hospitals was conducted. Patient data was obtained, including age, gender, location of lesions, staging and histological type of CRC. The(More)
Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs to combat fungal infections [Sobel, J.D. (2000) Clin Infectious Dis 30: 652], antifungal drug discovery is currently limited by both the availability of suitable drug targets and assays to screen corresponding targets. A functional genomics approach based on the(More)
Aquaporin-4 (AQP4) is the predominant water channel protein in the mammalian brain, and is mainly expressed in astrocytes. Besides its important role in water transport across the blood-brain barrier, our present study demonstrated that AQP4 deficiency impaired hippocampal long-term potentiation (LTP) and hippocampus-dependent memory formation, accompanied(More)