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CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan, China
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury
Itaconate is promising as a therapeutic candidate against ALI through inhibiting ferroptosis, one of the critical mechanisms contributing to sepsis-induced ALI.
Clinical Significance and Immunologic Landscape of a Five-IL(R)-Based Signature in Lung Adenocarcinoma
A robust prognostic IL(R)-based signature was provided which had the potential as a predictor for immunotherapy response to realize individualized treatment of LUAD and showed a strong prognostic ability.
Promising response to a PD-1 inhibitor (sintilimab) in non-small cell lung cancer
Abstract Rationale: Lung cancer is the cancer with the highest incidence and mortality in China and worldwide. Among them, 85% are non-small cell lung cancer (NSCLC). No previous reports have been…
Inflammatory Caspases Drive Pyroptosis in Acute Lung Injury
The review summarizes the relationship among inflammatory caspases, pyroptosis and acute lung injury and provides general directions and strategies to conduct further research.
The prognostic value of tumor-stromal ratio combined with TNM staging system in esophagus squamous cell carcinoma
The results indicated that TSR was a robust prognostic factor for ESCC patients and the novel TSNM staging system has a better discriminative ability than the conventional TNM staged system, especially for III stage patients.
Comparison of clinical characteristics of COVID-19 between elderly patients and young patients: a study based on a 28-day follow-up
Overall, the research compared the clinical characteristics of the two populations with different immune status and illustrated differentiated risk factors for death in them.
Nomogram for Predicting COVID-19 Disease Progression Based on Single-Center Data: Observational Study and Model Development
Clinical use of the nomogram may enable timely detection of potential critical patients with COVID-19 and instruct clinicians to administer early intervention to these patients to prevent the disease from worsening.
Survival Following Segmentectomy or Lobectomy in Patients With Stage IB Non-small-cell Lung Cancer
Overall survival (OS) and lung cancer-specific survival (LCSS) were assessed among patients who were performed lobectomy or segmentectomy and segmentectomy showed better OS and LCSS than segmentectomy for patients with a TS of >30 and ≤ 40 mm.
Toripalimab: the First Domestic Anti-Tumor PD-1 Antibody in China
It showed a satisfactory anti-tumor effect and long-term survival benefits in Chinese melanoma patients, while the combination of axitinib with toripalimab exhibited an impressive result in metastatic mucosal melanoma.