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The ongoing enhancement of mobile devices capabilities and advanced technologies has largely contributed to the huge increase of wireless traffic demand. Mobile network operators around the world are struggling to manage this new era of higher generation networks by finding new means and strategies to implement in order to meet the explosion in traffic(More)
Among the human genome, p53 is one of the first tumor suppressor genes to be discovered. It has a wide range of functions covering cell cycle control, apoptosis, genome integrity maintenance, metabolism, fertility, cellular reprogramming and autophagy. Although different possible underlying mechanisms for p53 regulation have been proposed for decades, none(More)
The proteins involved in breast cancer initiation and progression are still largely elusive. To gain insights into these processes, we conducted quantitative proteomic analyses with 21T series of breast cell lines, which include a normal, primary tumor and a metastatic tumor that were isolated from a single patient. Stable isotope labeling of amino acid in(More)
Co-transcriptional pre-mRNA processing relies on reversible phosphorylation of the carboxyl-terminal domain (CTD) of Rpb1, the largest subunit of RNA polymerase II (RNAP II). In this study, we replaced in live cells the endogenous Rpb1 by S2A Rpb1, where the second serines (Ser2) in the CTD heptapeptide repeats were switched to alanines, to prevent(More)
OBJECTIVES Certain components of the serotonin system have been known for some time to be risk factors for schizophrenia. Few studies have, however, focused on the association between the therapeutic responses to atypical antipsychotics, such as risperidone, and polymorphisms of the 5-HT3 receptor, the only ionotropic ligand-gated serotonin receptor, even(More)
A novel filter is proposed for edge-preserving decomposition of an image. It is different from previous filters in its locally adaptive property. The filtered image contains local means everywhere and preserves local salient edges. Comparisons are made between our filtered result and the results of three other methods. A detailed analysis is also made on(More)
In delay tolerant network, message delivery can be inspired by biological communication models in realizing encountering and delivering. One way of communications can be through “thrown box” where the messages can be left and collected by different nodes in mimicking pheromone-based communications. In thrown box based model, the box is viewed as message(More)