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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
Cystic renal diseases are caused by mutations of proteins that share a unique subcellular localization: the primary cilium of tubular epithelial cells. Mutations of the ciliary protein inversin causeExpand
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Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development
The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time‐resolved transcriptome analysis ofExpand
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Pou5f1/Oct4 Promotes Cell Survival via Direct Activation of mych Expression during Zebrafish Gastrulation
Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in establishment of pluripotency. Here we investigated the control of mycExpand
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Characterization of pip5k3 fleck corneal dystrophy-linked gene in zebrafish.
PIKfyve is a kinase encoded by pip5k3 involved in phosphatidylinositols (PdtIns) pathways. These lipids building cell membranes have structural functions and are involved in complex intracellularExpand
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Essential role for Pbx1 in corneal morphogenesis.
PURPOSE The Pbx TALE (three-amino-acid loop extension) homeodomain proteins interact with class 1 Hox proteins, which are master regulators of cell fate decisions. This study was performed toExpand
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Report of the European Zebrafish Principal Investigator Meeting in Padua, Italy, March 18–22, 2010.
Abstract The zebrafish community has been steadily growing in the last 20 years in Europe. Given the federal structure of Europe, this increase in zebrafish research generated a need for a strategicExpand
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Bigh3 is upregulated in regenerating zebrafish fin.
Zebrafish is a good model for studying regeneration because of the rapidity with which it occurs. Better understanding of this process may lead in the future to improvement of the regeneratingExpand
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Essential Role for Pbx 1 in Corneal Morphogenesis
PURPOSE. The Pbx TALE (three-amino-acid loop extension) homeodomain proteins interact with class 1 Hox proteins, which are master regulators of cell fate decisions. This study was performed toExpand
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