Blanka Pospíšilová

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Wnt signaling represents a highly versatile signaling system, which plays diverse and critical roles in various aspects of neural development. Sensory neurons of the dorsal root ganglia require Wnt signaling for initial cell-fate determination as well as patterning and synapse formation. Here we report that Wnt signaling pathways persist in adult sensory(More)
PURPOSE To evaluate the framework of drug information produced by public health and regulatory institutions in Europe. MATERIALS AND METHODS We carried out a short survey asking editors of ISDB bulletins of the European region to indicate the main sources of drug information provided by public health and regulatory authorities in their countries, the(More)
UNLABELLED The etiology of anaemia associated with tumours is multifactorial. One of the mechanisms of development of anaemia in tumours are so-called chronic diseases anaemias, the main feature of which is inadequate production of endogenous erythropoietin (EPO). The objective of the investigation was to test the effect of recombinant human erythropoietin(More)
Vascularization of some organs of rat following soman (O-pinacolyl methylphosphonofluoridate) intoxication was studied using scanning electron microscopy. Corrosion casts were prepared with commercially available methyl metacrylate monomer which was partly polymerized, supplemented with catalyst and accelerator and injected into the prewashed and fixed(More)
The localization of a serine exopeptidase--DPP IV--in the male and female submandibular gland of the mouse during gland postnatal development was studied histochemically in the light microscopic level. The present results suggest that localization of DPP IV is closely related to the postnatal differentiation and maturation of acini and male granular(More)
The presentation describes an interesting finding of healed multiple war cutting wounds in adult male skull. The examined dry skull belong to the extensive osteologic collection which comes from the abolished "Broumov Ossuary". The set encompasses skeletal remains of the population from the 13th to 18th centuries.
The work describes paleopathologic finding of brachycephaly deformation in 4 adult skulls, caused by premature coronal suture closure. Skulls come from the 35 pieces collection of craniostenoses, found in osteologic collection of 745 skulls from Broumov Ossuary. They were examined by cranioscopy, craniometry, x-ray and CT methods. Presence of brachycephaly(More)
Knowledge of topographic anatomy is essential prerequisite for any physician to be successful in professional career. That is why we pay special attention to topographic dissections completing course of normal human anatomy at our department. Dissection procedure is subjected to relatively rigid rules demanding removal of some superficial structures during(More)
The activity of succinate dehydrogenase (SDH) was examined histochemically in the parenchyma of murine submandibular gland (SMG) during postnatal development on light-microscopical level. In this study, SDH appears as a good marker of differentiating and mature striated ducts of both sexes and convoluted granular tubules of males. Enzyme activity in(More)