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Recent electrophysiological studies have shown that the human electroencephalographic mu rhythm is suppressed during the observation of actions performed by other persons, an effect that may be functionally related to the behaviour of so-called "mirror neurons" observed in area F5 of nonhuman primates. Because mirror neuron activity has been reported to be(More)
OBJECTIVE We characterised the spectral response of the EEG to median nerve stimulation using wavelet analysis, and compared the relative magnitudes of effect of several different action-observation conditions on the beta and mu 'rebound' rhythms. METHODS EEG responses to median nerve stimulation were recorded from 8 normal adult subjects during baseline(More)
We recorded 128-channel EEG from 16 participants while they observed, imitated, and self-initiated the precision grip of a manipulandum. Mu rhythm amplitudes were significantly lower during observation of a precision grip than during observation of a simple hand extension without object interaction. Scalp topographies for subtractions of observation,(More)
Long-term potentiation (LTP) is a candidate synaptic mechanism underlying learning and memory that has been studied extensively at the cellular and molecular level in laboratory animals. To date, LTP has only been directly demonstrated in humans in isolated cortical tissue obtained from patients undergoing surgery, where it displays properties identical to(More)
The cortical mechanisms of perceptual segregation of concurrent sound sources were examined, based on binaural detection of interaural timing differences. Auditory event-related potentials were measured from 11 healthy subjects. Binaural stimuli were created by introducing a dichotic delay of 500-ms duration to a narrow frequency region within a broadband(More)
This study was designed to test two hypotheses about binaural hearing: (1) that binaural cues are primarily processed in the hemisphere contralateral to the perceived location of a sound; and (2) that the two main binaural cues, interaural timing differences and interaural level differences, are processed in separate channels in the auditory cortex.(More)
OBJECTIVES The aim of this study was to examine the N300 and N400 effect to pictures that were semantically incongruous to a prior object name. Based upon theories of object identification, the semantic incongruity was manipulated to occur early or late in the object processing stream. METHODS High-density visual event-related potentials were measured in(More)
OBJECTIVE The aim of this study was to obtain a more detailed description of N400 scalp topography than has previously been reported. METHODS High-density (128 channel) visual event-related potentials were measured in an N400 paradigm using semantically incongruous sentence endings. RESULTS The stimuli elicited an N400 with a centroparietal scalp(More)
We investigated the role of cerebral motor structures during mental hand rotation. Neural activity was measured with event-related potentials (ERPs) in 16 healthy participants while they performed handedness judgments of visually presented hands. Mental rotation was associated with ERP amplitude modulations as early as 170 ms but most strongly during a time(More)
When inverted, thatcherized faces appear normal. This may be due to a decrease in configural and an increase in featural processing. It is not known whether this processing is continuous or reflects two distinct processing systems. Using event-related potentials (ERPs), we investigated the Thatcher effect on thatcherized and normal faces at varying(More)