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Recent electrophysiological studies have shown that the human electroencephalographic mu rhythm is suppressed during the observation of actions performed by other persons, an effect that may be functionally related to the behaviour of so-called "mirror neurons" observed in area F5 of nonhuman primates. Because mirror neuron activity has been reported to be(More)
OBJECTIVE We characterised the spectral response of the EEG to median nerve stimulation using wavelet analysis, and compared the relative magnitudes of effect of several different action-observation conditions on the beta and mu 'rebound' rhythms. METHODS EEG responses to median nerve stimulation were recorded from 8 normal adult subjects during baseline(More)
Long-term potentiation (LTP) is a candidate synaptic mechanism underlying learning and memory that has been studied extensively at the cellular and molecular level in laboratory animals. To date, LTP has only been directly demonstrated in humans in isolated cortical tissue obtained from patients undergoing surgery, where it displays properties identical to(More)
This study was designed to test two hypotheses about binaural hearing: (1) that binaural cues are primarily processed in the hemisphere contralateral to the perceived location of a sound; and (2) that the two main binaural cues, interaural timing differences and interaural level differences, are processed in separate channels in the auditory cortex.(More)
OBJECTIVES The aim of this study was to examine the N300 and N400 effect to pictures that were semantically incongruous to a prior object name. Based upon theories of object identification, the semantic incongruity was manipulated to occur early or late in the object processing stream. METHODS High-density visual event-related potentials were measured in(More)
We investigated the role of cerebral motor structures during mental hand rotation. Neural activity was measured with event-related potentials (ERPs) in 16 healthy participants while they performed handedness judgments of visually presented hands. Mental rotation was associated with ERP amplitude modulations as early as 170 ms but most strongly during a time(More)
In this experiment, the oscillatory responses of the MEG were characterized during the observation of four viewing conditions: (a) observation of mouth movements, (b) observation of a non-biological motion stimulus (a mechanical aperture opening and shutting), (c) observation of object-directed mouth movements and (d) observation of speech-like mouth(More)
We assessed lateralization of brain function during mental rotation, measuring the scalp distribution of a 400-600 ms latency event-related potential (ERP) with 128 recording electrodes. Twenty-four subjects, consisting of equal numbers of dextral and sinistral males and females, performed a mental rotation task under two response conditions (dominant(More)
OBJECTIVE Conventional whole-head MEG systems have fixed sensor arrays designed to accommodate most adult heads. However arrays optimised for adult brain measurements are suboptimal for research with the significantly smaller heads of young children. We wished to measure brain activity in children using a novel whole-head MEG system custom sized to fit the(More)
The time to decide if a letter is normal or backwards (mirror-reversed) increases as the letter is rotated away from the upright. It is widely accepted that this increase in time reflects the mental rotation of the stimulus to the upright orientation in order to determine the mirror-normal status of the stimulus. Although response times tend to be longer(More)