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Anticancer activity for 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) analogues and their abilities to interact with lymphoendothelial cell surface markers.
The structure of the anticancer agent 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) has been modified through SAR and by incorporating barbituric acid, pyridine, quinoline, andExpand
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Comparisons of the queen volatile compounds of instrumentally inseminated versus naturally mated honey bee (Apis mellifera) queens
Instrumental insemination is an attractive alternative to natural mating because specific genetic crosses can be made, thus producing colonies with desired traits. However, there are conflictingExpand
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Design, synthesis, and anticancer properties of 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone and analogues.
4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) has recently completed a phase I clinical trial in advanced cancer with minimal toxicity, and impressive objective responses were noted.Expand
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Preparation of tetrazoles from organic nitriles and sodium azide in micellar media
An effective method for the preparation of 5-substituted tetrazoles from the corresponding nitriles in micellar media is described. It was demonstrated that almost quantitative yields of tetrazolesExpand
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Preparation of 5-Alkylthio and 5-Arylthiotetrazoles from Thiocyanates Using Phase Transfer Catalysis
Abstract A very efficient method of preparation for 5-alkyl and 5-arylthiotetrazoles from the corresponding alkyl or aryl halides is described. The halides are first transformed into thiocyanatesExpand
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Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents
PurposeThe purpose of this investigation was to synthesize a series of carbonate and carbamate derivatives of 4-demethylpenclomedine (DM-PEN), the major plasma non-toxic metabolite of penclomedineExpand
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An AM1 and DFT‐AM1 computational study of methyl phenylpropiolate addition to 1‐phenyl‐3,4‐dimethylphosphole
The transition state structures for the addition of maleic acid anhydride and methyl phenylpropiolate to 1-phenyl-3,4-dimethylphosphole were generated with the AM1 semiempirical method. TheExpand
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