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Members of the myocyte enhancer binding factor-2 (MEF2) family of MADS (MCM1, agamous, deficiens, and serum response factor) box transcription factors are expressed in the skeletal, cardiac, and smooth muscle lineages of vertebrate and Drosophila embryos. These factors bind an adenine-thymidine-rich DNA sequence associated with muscle-specific genes. The(More)
In metal cutting, tool wear on the tool–chip and tool–workpiece interfaces (i.e. flank wear and crater wear) is strongly influenced by the cutting temperature, contact stresses, and relative sliding velocity at the interface. These process variables depend on tool and workpiece materials, tool geometry and coatings, cutting conditions, and use of coolant(More)
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