Bjorn E. Clausen

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Although skin dendritic cells (DCs) have been shown to directly present Ag to CD8(+) T cells after intradermal immunization with lentivectors, the contribution of the different skin DC subsets to this process remains unclear. Using langerin-diphtheria toxin receptor transgenic mice we demonstrated that ablation of langerhans cells and langerin-expressing(More)
A field experiment was carried out to measure drawdowns in observation wells and stream depletion flows that occurred when water was abstracted from a well beside a stream. The field data is analyzed herein to determine the aquifer transmissivity, T, the aquifer storage coefficient, S, and a streambed leakage parameter, lambda, by comparing measurements(More)
Dendritic cells (DCs) have been implicated in the pathogenesis of psoriasis but the roles for specific DC subsets are not well defined. Here we show that DCs are required for psoriasis-like changes in mouse skin induced by the local injection of IL-23. However, Flt3L-dependent DCs and resident Langerhans cells are dispensable for the inflammation. In(More)
Tension experiments in vacuum were performed on a monolithic Si 3 N 4 sample at 1375°C and a 20Vol% SiC p-Si 3 N 4 composite sample at 1400°C using the new SMARTS diffractometer at the Los Alamos Neutron Science Center. The deep penetration of neutrons facilitated these in-situ studies. In particular, the hkl-dependent strains were measured and the results(More)
Successful application of metal matrix composites often requires strength and lifetime predictions that account for the deformation of each constituent. However, the deformation of individual phases in composites usually differs significantly from their respective monolithic behaviors. For instance, generally little is known about the in-situ deformation of(More)
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