Bjoern Weissler

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Combining Positron Emission Tomography (PET) with Magnetic Resonance Imaging (MRI) results in a promising hybrid molecular imaging modality as it unifies the high sensitivity of PET for molecular and cellular processes with the functional and anatomical information from MRI. Digital Silicon Photomultipliers (dSiPMs) are the digital evolution in(More)
PET (positron emission tomography) with its high sensitivity in combination with MRI (magnetic resonance imaging) providing anatomic information with good soft-tissue contrast is considered to be a promising hybrid imaging modality. However, the integration of a PET detector into an MRI system is a challenging task since the MRI system is a sensitive device(More)
The full potential of simultaneous PET and MRI image acquisition, such as dynamic studies or motion compensation, can only be explored if the data of both modalities are temporally synchronized. These hybrid imaging systems are often realized as custom made PET inserts for commercially available MRI scanner. Unfortunately, the standard MRIs do not always(More)
In this work, we present an initial MR-compatibility study performed with the world's first preclinical PET/MR insert based on fully digital silicon photo multipliers (dSiPM). The PET insert allows simultaneous data acquisition of both imaging modalities and thus enables the true potential of hybrid PET/MRI. Since the PET insert has the potential to(More)
The combination of PET and MRI is a challenging task, since both imaging modalities might influence each other. For unaffected imaging performance, PET detectors need to be untouched by the MR operation (MR-compatible) and RF-silent. The latter requirement is demanding, as the digital Data Acquisition and Control Architecture (DACA) produce noise in the MRI(More)
The combination of Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) into a single device is being considered a promising tool for molecular imaging as it combines the high sensitivity of PET with the functional and anatomical images of MRI. For highest performance, a scalable, MR compatible detector architecture with a small form(More)
In modern positron emission tomography (PET) readout architectures, the position and energy estimation of scintillation events (singles) and the detection of coincident events (coincidences) are typically carried out on highly integrated, programmable printed circuit boards. The implementation of advanced singles and coincidence processing (SCP) algorithms(More)
The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a multi-modal imaging technique is considered very promising and powerful with regard to in vivo disease progression examination, therapy response monitoring and drug development. However, PET-MRI system design enabling simultaneous operation with unaffected(More)
Silicon based photon detectors make it nowadays possible to build highly integrated PET detectors for simultaneous PET/MRI. Although the operating principle of silicon photo-multipliers is believed to be insensitive to the strong magnetic fields inside MRI machines, the construction of an MRI compatible detector has to cover considerably more aspects of MRI(More)
2012, our group presented the Hyperion IID platform which uses PDPC's digitial SiPMs (DPC). In this work we use the same platform equipped with scintillator dimensions closer to a clinical application. This allows an investigation of the time of flight (ToF) performance of the platform and its behavior during simultaneous MR operation. We employ LYSO(More)