Björn Fredriksson

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The role of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) in the pathogenesis of colon cancer remains highly controversial. This study specifically silenced the PPAR-β expression in three colon cancer cell lines with different metastatic potentials. Although PPAR-β knockdown resulted in more malignant morphological changes, bigger colony sizes(More)
BACKGROUND In Sweden, the number of people serving life sentences has steadily increased. To date, few studies have examined the recidivism rate or the predictive validity of different risk assessment instruments in this group. AIMS Our aim was to test the predictive validity among inmates serving life sentences of two different instruments used for(More)
Although typically described as reliable and valid, the Psychopathy Checklist-Revised (PCL-R) has come under some criticism by researchers in the last half-decade due to evidence of poor interrater reliability and adversarial allegiance being reported in applied settings in North America. This study examines the field reliability of the PCL-R using a(More)
It is known that many male juvenile delinquents commit violent crimes while intoxicated with flunitrazepam (FZ), often in combination with alcohol or other drugs. We have also noted the combined abuse of FZ with, for example, alcohol in male forensic psychiatric patients. Our objective was to study violent behavior, impulsive decision-making, and amnesia in(More)
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