Bishnupriya Bhattacharya

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Dataflow has proven to be an attractive computation model for programming digital signal processing (DSP) applications. A restricted version of dataflow, termed synchronous dataflow (SDF), that offers strong compile-time predictability properties, but has limited expressive power, has been studied extensively in the DSP context. Many extensions to(More)
Dataflow programming has proven to be popular for representing applications in rapid prototyping tools for digital signal processing (DSP); however, existing dataflow design tools are limited in their ability to effectively handle dynamic application behavior. In this paper, we develop efficient quasi-static scheduling techniques for a broad class of(More)
The release of Bluetongue virus (BTV) and other members of the Orbivirus genus from infected host cells occurs predominantly by cell lysis, and in some cases, by budding from the plasma membrane. Two nonstructural proteins, NS3 and NS3A, have been implicated in this process. Here we show that both proteins bind to human Tsg101 and its ortholog from(More)
  • Xing Zhang, Mark Boyce, +4 authors Z Hong Zhou
  • Proceedings of the National Academy of Sciences…
  • 2010
Bluetongue virus (BTV) is transmitted by blood-feeding insects (Culicoides sp.) and causes hemorrhagic diseases in livestock. BTV is a nonenveloped, double-stranded RNA (dsRNA) virus with two capsids: a well-studied, stable core enclosing the dsRNA genome and a highly unstable, poorly studied coat responsible for host cell attachment and entry. Here, based(More)
Bluetongue virus (BTV) particles consist of seven structural proteins that are organized into two capsids. In addition, BTV also encodes three non-structural (NS) proteins of which protein 2 (NS2) is the RNA binding protein and is also the major component of virus encoded inclusion bodies (VIBs), which are believed to be virus assembly sites. To investigate(More)
The VP2 outer capsid protein Bluetongue Virus (BTV) is responsible for receptor binding, haemagglutination and eliciting host-specific immunity. However, the assembly of this outer capsid protein on the transcriptionally active viral core would block transcription of the virus. Thus assembly of the outer capsid on the core particle must be a tightly(More)
Bluetongue virus (BTV) is a nonenveloped double-stranded RNA virus belonging to the family Reoviridae. The two outer capsid proteins, VP2 and VP5, are responsible for virus entry. However, little is known about the roles of these two proteins, particularly VP5, in virus trafficking and assembly. In this study, we used density gradient fractionation and(More)
Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis, indicating that these viruses may also utilize alternate means for egress. Moreover, it appears that complex,(More)
UNLABELLED Bluetongue virus (BTV), a member of the Orbivirus genus in the Reoviridae family, is a double-capsid insect-borne virus enclosing a genome of 10 double-stranded RNA segments. Like those of other members of the family, BTV virions are nonenveloped particles containing two architecturally complex capsids. The two proteins of the outer capsid, VP2(More)