Birgit S Jacobs

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Psychosis and other mental illnesses are common in HIV-infected patients. Olanzapine is one of the preferred antipsychotic agents for the treatment of schizophrenia. Olanzapine is primarily metabolised by CYP1A2 and uridine diphosphate glucuronosyltransferase (UGT). High-dose ritonavir has been shown to increase olanzapine elimination through induction of(More)
It is widely known that both antiretroviral agents for human mmunodeficiency virus (HIV) infection and novel anti-hepatitis virus (anti-HCV) agents may cause and/or be the victim of rug–drug interactions [1]. Both healthy volunteer and phase 2 linical studies can guide us to select appropriate regimens when oth infections need to be treated simultaneously.(More)
Polyethylene glycol-(PEG)based laxatives are the most prescribed osmotic oral laxatives and proven to be safe in children with chronic constipation. 1 However, little is known about the improper administration of the drug by infusion. We report a case of unintentional intravenous PEG 4000 infusion without any local or systemic toxic effects. A 5-year-old(More)
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