Learn More
OBJECTIVE To explore the effects of acupuncture at HT7 on different cerebral regions in a rat model of Alzheimer's disease (AD) with the application of (18)F-2-fluoro-deoxy-D-glucose positron emission tomography (FDG-PET). METHODS Sixty Wistar rats were included after undergoing a Y-maze electric sensitivity test. Ten rats were used as a healthy control(More)
OBJECTIVE This study was designed to detect the brain glucose metabolism in rat models of Alzheimer's disease (AD) by the application of (18)F-2-fluoro-deoxy-d-glucose positron emission tomography ((18)F-FDG-PET) and to provide new insights for the early detection of AD. METHODS Forty Wistar rats were randomly divided into 2 groups. Fifteen sham-operated(More)
The mechanical behavior of ankle ligaments at the structural level can be characterized by force-displacement curves in the physiologic phase up to the initiation of failure. However, these properties are difficult to characterize in vitro due to the experimental difficulties in replicating the complex geometry and non-uniformity of the loading state in(More)
OBJECTIVE The goal of this study was to investigate the influence of the occupant characteristics on seat belt force vs. payout behavior based on experiment data from different configurations in frontal impacts. METHODS The data set reviewed consists of 58 frontal sled tests using several anthropomorphic test devices (ATDs) and postmortem human subjects(More)
OBJECTIVE The objective of this study was to discuss the influence of the pre-impact posture to the response of a finite element human body model (HBM) in frontal impacts. METHODS This study uses previously published cadaveric tests (PMHS), which measured six realistic pre-impact postures. Seven postured models were created from the THUMS occupant model(More)
Ligament sprains account for a majority of injuries to the foot and ankle complex, but ligament properties have not been understood well due to the difficulties in replicating the complex geometry, in situ stress state, and non-uniformity of the strain. For a full investigation of the injury mechanism, it is essential to build up a foot and ankle model(More)
OBJECTIVE Pedestrian lower extremity represents the most frequently injured body region in car-to-pedestrian accidents. The European Directive concerning pedestrian safety was established in 2003 for evaluating pedestrian protection performance of car models. However, design changes have not been quantified since then. The goal of this study was to(More)
OBJECTIVE The lower extremity of the occupant represents the most frequently injured body region in motor vehicle crashes. Knee airbags (KABs) have been implemented as a potential countermeasure to reduce lower extremity injuries. Despite the increasing prevalence of KABs in vehicles, the biomechanical interaction of the human lower extremity with the KAB(More)
OBJECTIVE Occupants with extreme body size and shape, such as the small female or the obese, were reported to sustain high risk of injury in motor vehicle crashes (MVCs). Dimensional scaling approaches are widely used in injury biomechanics research based on the assumption of geometrical similarity. However, its application scope has not been quantified(More)
The purpose of this study was to determine the long-time and transient characteristics of the moment generated by external (ER) and internal (IR) rotation of the calcaneus with respect to the tibia. Two human cadaver legs were disarticulated at the knee joint while maintaining the connective tissue between the tibia and fibula. An axial rotation of 21° was(More)