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OBJECTIVE This research aimed to investigate the correlation between glutathione S-transferase P1 (GSTP1) gene exon5 A/G polymorphism and chronic obstructive pulmonary disease (COPD) susceptibility in northern Chinese population of Han nationality living in Beijing. METHODS The genotypes of 97 COPD patients and 67 smoking control subjects without COPD(More)
OBJECTIVE We investigated whether polymorphism in gene for microsomal epoxide hydrolase (mEH) has any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease. METHOD The genotypes of 55 patients with COPD and 52 healthy smoking control subjects were tested with polymerase chain reaction followed by restriction(More)
A new extraction technique, high hydrostatic pressure extraction (HHPE), was used to obtain polyphenols from green tea leaves. Various experimental conditions, such as different solvents (acetone, methanol, ethanol and water), pressure (100, 200, 300, 400, 500, 600 MPa), holding time (1, 4, 7, 10 min), ethanol concentration (0-100% mL/mL), and liquid/solid(More)
OBJECTIVE To study whether familial aggregation exists in pulmonary function impairment and COPD. METHODS Pulmonary function, smoking habits, history of occupational dust exposure and clinical manifestation among 117 children of 59 smokers with COPD and 55 children of 28 control smokers without COPD. A multivariate linear regression analysis was carried(More)
OBJECTIVE To assess the risk factors correlating to the likelihood for airflow obstruction among first-degree children of chronic obstructive pulmonary disease (COPD) patients and whether familial aggregation of pulmonary function abnormality exists. METHODS Fifty-nine smokers with COPD and 28 smokers without COPD as control and all their children(More)
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